A LOW-COST AND EASY TO USE SORTING DEVICE FOR THE SEPARATION OF EXTRACELLULAR VESICLES FROM COMPLEX FLUIDS
Résumé
We propose a simple microfluidic device able to separate extracellular vesicles (EVs and exosomes) from a complex sample using a low cost and ready-to-use hydrodynamic filtration lab on chip. We have shown the efficient separation of biofunctionnaliszed nanoparticles mimicking platelets derived EVs (diameter 700 nm) from synthetic samples and from diluted whole blood. Separation yield and recovery yield have been measured > 96% and 100% respectively.
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TAS2021_A low-cost and easy to use sorting device for the separation of extracellular vesicles from complex fluids_PILLEMONT.pdf (1.14 Mo)
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