A LOW-COST AND EASY TO USE SORTING DEVICE FOR THE SEPARATION OF EXTRACELLULAR VESICLES FROM COMPLEX FLUIDS - LAAS - Laboratoire d'Analyse et d'Architecture des Systèmes Access content directly
Conference Papers Year : 2021

A LOW-COST AND EASY TO USE SORTING DEVICE FOR THE SEPARATION OF EXTRACELLULAR VESICLES FROM COMPLEX FLUIDS

Abstract

We propose a simple microfluidic device able to separate extracellular vesicles (EVs and exosomes) from a complex sample using a low cost and ready-to-use hydrodynamic filtration lab on chip. We have shown the efficient separation of biofunctionnaliszed nanoparticles mimicking platelets derived EVs (diameter 700 nm) from synthetic samples and from diluted whole blood. Separation yield and recovery yield have been measured > 96% and 100% respectively.
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Dates and versions

hal-03514431 , version 1 (06-01-2022)

Identifiers

  • HAL Id : hal-03514431 , version 1

Cite

Lyne Pillemont, Daniel Guneysu, Wilfrid Boireau, Céline Elie-Caille, Anne Marie Gué. A LOW-COST AND EASY TO USE SORTING DEVICE FOR THE SEPARATION OF EXTRACELLULAR VESICLES FROM COMPLEX FLUIDS. MicroTAS 2021, Amy E. Herr, Joel Voldman, Oct 2021, Palm Springs, United States. ⟨hal-03514431⟩
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